Here are some expert-approved tips and practices to help you get the most out of collagen supplements. (1) Choose one with vitamin C. Collagen works best when integrated with vitamin C because your body cannot effectively produce collagen without the antioxidant. (2) Time of day doesn’t really matter. You should take your collagen supplements whenever it’s easy and convenient for you. (3) Ensure your collagen formula adheres to clean beauty standards and doesn’t include artificial colors, flavors, and known allergens.